Abstract

Objective To study the effect of comprehensive nursing on the cognitive level,mental status,and the ability to live of patients with Alzheimer's disease.Methods Totals of 120 patients with Alzheimer's disease were randomly divided into two groups,each group of the 60 patients.The patients in the control group received conventional care,while the patients in the observation group were given comprehensive nursing.Then,two groups were investigated with the mini mental state examination scale (MMSE),Hamilton rating scale for depression (HAMD),Hamilton rating scale for anxiety (HAMA),and activities of daily living scale (ADL),before and after the intervention.Results No significant difference was found in the scores of patients of the MMSE,ADL,HAMA,and HAMD between two groups before the intervention (P > 0.05).After the intervention,significant difference was found between control group and observation group in the MMSE score [(11.1 ±3.2) vs (23.4 ±2.7);t =22.793,P <0.05],ADL score[(24.1 ±4.7) vs (20.2 ± 1.3) ;t =15.251,P < 0.05],HAMA score [(15.0 ± 2.1) vs (7.4 ± 1.6) ;t =22.298,P < 0.05],and HAMD score [(15.8 ± 3.9) vs (7.5 ± 1.4);t =15.516,P < 0.05].No significant difference was found in the change of control group before and after the intervention (P > 0.05),while significant difference was found in the observation group(P <0.05).Conclusions The comprehensive nursing can improve the level of awareness,mental state and living ability of patients with Alzheimer's disease,and improve the patient's quality of life. Key words: Alzheimer's disease ; Nursing; Cognitive ; Mental state; Living ability

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