EFFECT OF COMBINATED APPLICATION OF PROBIOTIC AND ENTEROSORBENT ON THE DYNAMICS OF CORTISOL IN CHICKENS IN THE EARLY POSTEMBRIONIC PERIOD

Abstract

The research is devoted to the study of chickens’ cortisol dynamics at an early stage ofpost-embryonic development with the use of probiotics such as zoonorm, enterosorbent based on polymethylsilxane polyhydrate and their complex. To achieve the goal, 4 groups of analogue chickens were formed, 1 was a control group, 2 - received a probiotic in a mixture with feed at a dose of 0.2 g per head in morning feeding; 3 - 0.3% weight enterosorbent 2 hours after evening feeding; 4 - a combination of two preparations at the appropriate time. The introduction of drugs was carried out from 5- to 25-day age. All the indicators were analyzed in 5-, 15-, 25- and 35-day chicks. As a result of the research, chicks in all groups showed an increase in cortisol concentrations. In the control group a stable growth of the indicator was observed, which reached a maximum in 35 days, an increase in the concentration of the hormone by 41.6% was accompanied by an increase in glucose to 14.6 to 0.5 mmol/L, a decrease in cholesterol and triglycerides. In chicks 2 and 3 groups the highest value of cortisol is noted in 25 days, 4 - in 15 days. In 2 and 3 groups, with maximum cortisol levels, glucose concentrations were 14.64 and 14.91 mmol/L, with a marked decrease in triglycerides and cholesterol. In the 4th group of 15-day-old chicks, an 8.4% increase in cholesterol and triglycerides resulted in a 37.3 and 68.9% decrease in cholesterol and triglycerides. At the end of the experiment, the 4th group was found to reduce cortisol to 5.07 nmol/L, glucose to 12.32 to 0.13 mmol/L, and a relative increase in triglycerides. In conclusion, the relationship between synthesis of cortisol, cholesterol, triglycerides, glucose and their metabolism was confirmed. There has been a marked reduction in the influence of stress factors and increased resistance of chickens with the complex use of probiotic and enterosorbent.