Abstract
Different concentrations of cold aqueous extract Ficus carcia leaves were studied on the levels of glucose, cholesterol, triglycerides, total lipids, Aspartate amino transferase (AST) and Alanine amino transferase (ALT) activity and total protein in the serum and in the liver glycogen level and total protein in the liver and heart of the normal rats. 25 male albino wistar rats derived were used, with age 3-4 month, and weight 225-300 g. The rats were divided randomly into five groups. The first group was injected with distilled water and consumed the control group. The second, third, fourth and fifth groups were injected intraperitonealy with 100, 200, 300, and 400 mg/kg B.W with aqueous extract of Ficus carcia leaves. The blood, liver, and heart tissues were collected. The statistical results showed a significant decrease in the glucose, cholesterol, triglycerides and total lipids. While a significant increase in the Aspartate amino transferase (AST) and Alanine amino transferase (ALT) activity was showed in group 5of both compared with the control group (P < 0.05). In the tissues a significant reduction showed in the liver glycogen, for all concentration of the injected extract while insignificant differences were showed in the liver and heart total protein compared with the control group (P < 0.05). It was concluded that the cold aqueous extract of ficus carcia leaves has a biochemical role in the regulation and controlling the metabolic reaction through decreasing the glucose and lipids levels.
Highlights
The fig tree (Ficus Carcia) is one of the most important fruit trees.Grows fast to 10 foot tall, tolerates summer heat and full sun
1.Effect of cold aqueous extract of Ficus carcia Leaves on serum glucose: The results in table (1) and fig (1) showed that serum glucose was significantly decrease in group 2 and 3 that injected with 100 and 200 mg/kg B.W of leaves extract respectively, compared with the control group (P
This result was similar to that obtained by Serraclava et al(1998) who demonstrated the hypoglycemic properties of Ficus leaves in the rats this result was similar to the results obtained by Day (1995) Torres et al(1999), and Pereze et al(2003), who explained the hypoglycemic effect of the Ficus carcia leaves extract,on the diabetic rats
Summary
The fig tree (Ficus Carcia) is one of the most important fruit trees.Grows fast to 10 foot tall , tolerates summer heat and full sun. It Can with stand drough Conditions , and grows best in well- drained areas (Corner , 1995) Ficus carcia Contain number of natural enzymes such as B- gluconase , Cellulase , xylonase , and proteolytic enzymes ( Kramer and Whitaker,1964) its protein content showed large differences ( Sorensen,1996) and has low fat content (1-3)% of dry matter (Francesch, 1995).its starch about (10-15) % of dry matter with amylopectin more than amylose. About the effect of ficus carcia , so our aim of this research is to explain the biochemical effect of the leaves aqueous extract of the local ficus carcia on the rats
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