Abstract
Objectives: Numerous reports have demonstrated the beneficial effects of co-culture on embryo development such as an improved embryo quality and increased blastulation rate. Although the probable action mechanism of co-culture has been suggested in several ways, there is no evidence as yet for the correct mechanism of co-culture effect. The aim of this study is to elucidate the mechanism for the action of co-culture using a co-culture system of mouse 1-cell embryos with human oviductal epithelial cells.
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