Abstract
During incubation of the lysosomal fraction of the albino mouse liver withClostridiumperfringens type A toxin and also with the toxin and filtrate of a broth culture ofClostridiumbutyricum, and increase in the specific acid phosphatase activity was observed. The action ofC.perfringer toxin on the lysosomal membrane was potentiated under the influence of metabolic products ofC.butyricum. Potentiation of the action ofC.perfringens toxin on the lysosomes was due to thermostable substances in theC.butyricum filtrate.
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