Abstract
Cigarette smoke (CS) is a major risk factor for pulmonary diseases. Alveolar macrophages (AM) are known to play an important role in the lung immune system. Cryptomeria Japonica pollen (CJp) is known as pollen allergen but not cleared to immune response in the lung. Also, it is not fully understood the relationship of CS and CJp on immune cells in the lung. Therefore, we investigated the effects of CS and CJp on immune cells response in the lung. Mice were exposed to CS during 10 days. The next day, mice were inhaled 600μg of CJp.
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