Abstract
The effect of cholecystectomy on bile flow and composition in response to food was studied using a fistula which permitted collection of bile after it passed through the choledochoduodenal sphincter. The feeding responses for bile flow rate, bicarbonate concentration, and bicarbonate output were unchanged by cholecystectomy. Bile salt concentration and output increased markedly after feeding when the gallbladder was present, but remained at basal prefeeding levels after cholecystectomy.
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