Abstract
Dental caries and erosion are caused by demineralization, which occurs as a result of imbalanced tooth remineralization. Chitosan contains highly acid-reactive hydroxyl and amino groups and thus may affect the solubility of tooth enamel and mechanisms associated with increased environmental pH in the oral cavity. In this study, we examined the effects of chitosan on 11 extracted incisive and pre-molar teeth. The teeth were categorized into baseline group, negative control, acid plus chitosan, and chitosan treatment groups. Compared to the negative control, the teeth subjected to acid plus chitosan treatment led to an increased pH and decreased calcium concentration. It can be concluded that chitosan inhibits the tooth enamel demineralization process in vitro.
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