Abstract
The purpose of this study was to assess for an association between higher body mass index and disease severity, morbidity and mortality in children admitted for an acute respiratory distress and failure. A single-institution retrospective cross-sectional study performed in the United States evaluating paediatric patients, 2-20years of age, admitted for diagnoses related to acute respiratory distress and acute respiratory failure. Main outcomes include disease severity as assessed using the respiratory component of the Paediatric Early Warning Score (PEWS) with adjustment for altered mental status (Resp-PEWS+AMS), hospital or intensive care length of stay (LOS) and death. Children with obesity made up 42/334 (13%) of the cohort. There was no significant difference in Resp-PEWS+AMS between obese and non-obese cohorts (mean of 0.93, {standard deviation 1.11} vs. 1.13 {1.35}, range 0-6, rank sum p=0.46). There was no significant difference in overall hospital LOS or intensive care LOS. Multivariate analysis including diagnosis as a control variable did not change the results. We found that body habitus was not an independent factor for illness severity or clinical outcomes.
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