Abstract

This study was conducted to investigate the effect of cheonggukjang made with soybean germinated under dark and light conditions on lipid content and fecal neutral steroids in rats fed with a high cholesterol diet. Rats were divided into 4 groups: high cholesterol diet (HC); high cholesterol diet containing normal cheonggukjang (HNC); high cholesterol diet containing cheonggukjang made with soybean germinated under dark condition (HDC); high cholesterol diet containing cheonggukjang made with soybean germinated under light condition (HLC). Dietary supplementation with light-reacted cheonggukjang decreased hepatic triglycerides, compared with the other groups. Fecal excretion of total lipids and triglycerides increased when fed with cheonggukjang made with soybean germinated under light condition. Fecal excretion of coprostanol, cholesterol, and coprostanone tended to increase in the cheonggukjang-supplemented groups. These results suggest that dietary supplementation with cheonggukjang made with germinated soybean might prevent hyperlipidemia by improving the lipid metabolism through decreasing the liver triglycerides contents and increasing fecal excretion of triglycerides.

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