Abstract
In nucleon-nucleon collisions, a charged particle's multiplicity fluctuates. We have studied the effect of multiplicity fluctuation on flow harmonics in nucleus-nucleus collisions in event-by-event hydrodynamics. Assuming that the charged particle's multiplicity fluctuations are governed by the negative binomial distribution, the Monte Carlo Glauber model of initial condition is generalized to include the fluctuations. Explicit simulations with the generalized Monte Carlo Glauber model initial conditions indicate that the multiplicity fluctuations do not have a large effect on the flow harmonics.
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