Abstract

CATECHOLAMINES, especially noradrenaline, are regarded as central neuro-humoral agents of ergotropic character1–3. Notwithstanding, parenterally injected adrenalin has a depressive effect in intact animals, at least in relatively high doses, causing, in certain conditions, even sopor or general analgesia. Similar effects have been observed also after injections of catecholamines into the sub-arachnoideal space, the ventricles or the cerebral tissue2.

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