Abstract
One of two groups of rabbits were exposed to carbon monoxide (CO, 50 ppm by volume) for 24 hr continuously for 8 weeks, whereas the second breathed ambient air. Percentage oxyhemoglobin (HbO 2), percentage hemoglobin (g/100 ml), and percentage carboxyhemoglobin (COHb) were monitored in both groups. The mean percentage carboxyhemoglobin increased up to 30.91% at the end of the eighth week. Tests of fibrinolysis were monitored and showed acceleration of the whole-blood clot lysis, euglobulin lysis, and increase in whole-blood clotting time. A fibrin plate test confirmed the increased lysis, and serum fibrin/fibrinogen degradation products were elevated in the CO-exposed animals. No changes were observed in the same tests in the rabbits exposed to ambient air.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
