Abstract
1. 1. Nicotine at 10 mM, but not caffeine or theophylline, reduced by 20% the overshoot of the Na +-dependent d-glucose transport in ratjejunal brush border membrane vesicles. 2. 2. Since nicotine did not affect the transport of Na +, its inhibition on Na +-dependent d-glucose transport must be due to a direct effect upon the d-glucose transport system. 3. 3. Folate transport in these membrane vesicles was found to a be a free diffusion process at pH 7.4. 4. 4. Neither caffeine, theophylline nor nicotine has any effect on folate transport.
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