Abstract
Objective:To investigate the effect of bone graft volume on postoperative fusion and symptom improvement in lumbar posterior lumbar fusion and internal fixation.Methods:A total of 82 patients receiving pedicle screw rod system internal fixation with Cage bone graft fusion in the First Hospital of Baoding City, Hebei Province were selected and randomly divided into three groups. The excised autologous laminar bones were bitten into different sizes of bone fragments. And different sizes of bone grafts were implanted during the operation. Group-A (n=28) was implanted by bone graft granule with the average volume of 0.2 cm3, Group-B (n=27) was implanted by bone graft granule with the average volume of 0.1 cm3, and Group-C (n=27) was implanted by bone graft granule with the average volume of 0.05 cm3. The bone graft granule volume, clinical effect, bone graft fusion rate and intervertebral space height were compared.Results:The three groups had significantly different bone graft granule volumes (P<0.05), but similar intervertebral bone graft total volumes and Cage heights (P>0.05). In the final follow-up, VAS and ODI of low back pain and two lower limbs pain significantly reduced compared with those before surgery (P<0.05), but the three groups had similar results (P>0.05). The bone graft fusions of Group-B one and two years after surgery were significantly higher than those of Group-A and Group-C, and the values of Group-A exceeded those of Group-C (P<0.05). In the final follow-up, the intervertebral space height change of Group-B was significantly smaller than those of Group-A and Group-C (P<0.05).Conclusion:Size of bone graft granule has no significant effect on postoperative symptoms. However, middle-sized volume bone graft granule (0.1 cm3/granule) showed increased postoperative intervertebral fusion rate and reduced intervertebral space height loss in our study.
Highlights
Lumbar vertebrae is a key hub for human trunk activity, and almost all physical activity increases the burden on the lumbar spine
The purpose is to restore the normal alignment of the lumbar spine, relieve the symptoms of lumbar nerve root compression and rebuild the stability of the spine
Patients with pedicle screw system and Cage bone grafting were divided according to the intraoperative interbody bone graft volume, and their clinical effects were compared, and evaluate the effects of bone graft granule volume on postoperative fusion
Summary
Lumbar vertebrae is a key hub for human trunk activity, and almost all physical activity increases the burden on the lumbar spine. Spinal pedicle screw rod system internal fixation with bone graft fusion and posterior interbody cage (abbreviated as Cage therafter) with rigid fixation in the preliminary stage has been widely used to treat lumbar intervertebral disc protrusion, spinal stenosis, and other lumbar degenerative diseases.[1] The purpose is to restore the normal alignment of the lumbar spine, relieve the symptoms of lumbar nerve root compression and rebuild the stability of the spine. It has been reported in the literature that posterior lumbar interbody fusion (PLIF) has obvious advantages in biomechanics and clinical practice.[2,3] Cloward[4] first reported the use of posterior interbody fusion in the laminectomy. Patients with pedicle screw system and Cage bone grafting were divided according to the intraoperative interbody bone graft volume, and their clinical effects were compared, and evaluate the effects of bone graft granule volume on postoperative fusion
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
