Abstract
This study was to investigate the influence of bone cement implantation on haemodynamics and the preventive effect of epinephrine hydrochloride on pulmonary embolism in elderly patients with cemented semihip replacement. 128 patients were retrospectively analyzed. The patients were treated with (group A, 64 cases) or without (group B, 64 cases) epinephrine hydrochloride saline. The monitoring indicators included systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), and pulse oxygen saturation (SPO2). The indicators of the two groups were compared before and 1, 2, 3, 4, 5, 6, 7, 8, 9, and 10 minutes after bone cement implantation. Analysis of variance and SNK-q test were used for the statistical analysis. Blood pressure and SPO2 of group B decreased with statistical difference (P < 0.05) and HR increased without statistical significance, comparing with those of group A. In group A, SBP, DBP, MAP, HR, and SPO2 after bone cement implantation did not change significantly at each time point comparing with before implantation (P > 0.05). Bone cement implantation has significant influence on hemodynamics in elderly patients with hemiarthroplasty. Flushing the bone marrow cavity with saline epinephrine hydrochloride is an effective measure to reduce the incidence of bone cement pulmonary embolism.
Highlights
Femoral neck fractures comprise 50% of geriatric hip fractures and are associated with radial and humeral fractures [1]
Hemiarthroplasty, and total hip replacement could be considered as appropriate solutions [3]
Pulmonary embolism is often reported in a variety of clinical studies and animal experiments of hemiarthroplasty [8,9,10]
Summary
Femoral neck fractures comprise 50% of geriatric hip fractures and are associated with radial and humeral fractures [1]. It may result from falls, especially in elderly and osteoporotic females. With the increasing of aging population, the rate of hip fractures is expected to increase from less than 2 million in 1990 to more than 6 million by 2050 [2]. Surgical management of displaced subcapital fractures of the femoral neck continues to be challenging. Hemiarthroplasty, and total hip replacement could be considered as appropriate solutions [3]. Total hip arthroplasty and hemiarthroplasty are effective methods to treat femoral neck fractures in elderly patients currently [4]
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