Effect of BMI and Its Optimal Cut-Off Value in Identifying Hypertension in Uyghur and Han Chinese: A Biethnic Study from the China National Health Survey (CNHS).

Huijing He,Lize Pa,Hebuli Mu,Ning Tao,Yashengjiang Abudurexiti,Adili Simayi,Li Pan,Guangliang Shan

doi:10.1155/2018/1508083

Abstract

Objective The effect of adiposity on hypertension among Uyghur Chinese is not clear. This study aimed to compare the effect of BMI and its optimal cut-off value in identifying hypertension in Uyghur and Han adults in China. Methods By using a multistage stratified sampling method, 3072 Uyghur and 3195 Han adults underwent questionnaire interview, physical examination, and biochemical tests. Age- and sex-standardized prevalence of hypertension was calculated. Adjusted odds ratios for adiposity associated with hypertension were estimated. ROC analyses were used for assessing the ethnic and sex specific optimal BMI cut-off values in identifying hypertension. Results Both in Uyghur and Han, increased BMI was consistent with the elevated systolic and diastolic blood pressure. Although more Uyghur were overweight/obese, their standardized prevalence of hypertension (17.87%) was lower than that of Han (20.28%). Han adults had 1.42 times odds than Uyghur of hypertension. The adjusted ORs of overweight and obesity were 2.67 and 6.04 in Uyghur and 2.74 and 7.58 in Han. In male, the optimal cut-off values of BMI identifying hypertension in Uyghur and Han were 24.6 kg/m2 and 24.9 kg/m2 , respectively, but the correspond values in Uyghur and Han females were 27.2 kg/m2 and 25.0 kg/m2. Conclusions Adiposity had strong effect on hypertension, but this effect was less strong in Uyghur female than in Han female.

Highlights

World widely, hypertension is a major public health problem and is considered the greatest attributable risk factors for death [1]
Demographic and Clinical Characteristics in Uyghur and Han Participants. 2928 Uyghur (1028 males and 1900 females) and 3097 Han adults (1255 males and 1842 females) aged 20-80 years were included for analysis
The age- and sex-standardized hypertension prevalence was 17.87% in Uyghur, and 20.28% in Han

Summary

Introduction

Hypertension is a major public health problem and is considered the greatest attributable risk factors for death [1]. Blood pressure control is a national public health priority in China [2], the prevalence of hypertension in Chinese adults aged 35-75 was 44.7% in 2017 [3]. Excess adiposity is a well-established risk factor for major chronic diseases [4], and it is generally accepted that being overweight or obese increases the risk of the development of hypertension [5,6,7]. Previous studies have explored the disparities between Uyghur and Han on prevalence of several chronic diseases such as type 2 diabetes, dyslipidemia, and hypertension [11,12,13,14]. Gu’s study revealed a higher prevalence in Uyghur adults than Han [13], in contrast with Tao’s study

Methods

Results

Conclusion