Abstract

Moderate blood loss (20 ml/kg) increases NO content in the intestinal mucosa and muscle layer, and especially, in the liver, as revealed byin vivo nitric oxide (NO) binding with Fe2+-diethyldithiocarbamate complex yielding paramagnetic mononitrosyl iron complexes. Enhanced NO synthesis after blood loss prevents vascular spasm in the mucosa, thus maintaining blood circulation and effective absorption in the small intestine.

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