Effect of Blood Groups and Complications on Orofacial Measurements of B Thalassemia Adult Patients

Abstract

Background: ?- thalassaemia is a common hereditary disorders in Iraq and worldwide .with differenttreatment schemes,, including blood transfusion, iron chelation and splenectomy, patients with B thalassemiamay develop different skeletal changes. Limited studies link these complications with orofacial changes,This study aimed to evaluate the orofacial dimensions in ?- thalassemia patients with age, gender, bloodgroups, splenectomy and cholecystectomy and to assist surgeons for planning their future intervention.Method: This study was conducted on 130 ß-thalassemia patients of both gender,,and two age categories (20-30 yrs), & (21-40 yrs), five orofacial measurements (face,eyes,nose,mouth and ears) and sixteen parameterswere measured and calculated for differences,P value is estimated,data analysis were done by using Chisquare test and SPSS version 20Results: Significant findings were found for mandibular width and mouth width at older age group (31-40years), the nasal width and ear height are more in male, patients with splenectomy have significance forlower 1\3 face and ear width. Cholecystectomy increase eye length measurments and ear height but forblood groups the P ? 0.05Conclusions: Orofacial bone changes are pronounced in ?- thalassaemia with distinct findings regarding sexdimorphism, older are more prone to have variations, earlier splenectomy is advisable,cholecystectomy isbetter choice for symptomatic patients, blood groups have no significance.