Abstract
OBJECTIVE: To investigate the effects of an endocrine disruptor, bisphenol A (BPA), on human endometrial stromal fibroblast in vitro. BPA has a variety of endocrine-like effects on different cell and tissue types. However, studies on the effect of BPA on endometrium, and in particular human endometrium, are very limited. Herein, we evaluated the effects of BPA on the expression of several genes involved in estrogen metabolism, and on human endometrial stromal fibroblast (hESF) differentiation.
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