Abstract
This study was initiated to evaluate the effect on contractility of the longitudinal and circular muscles of the canine gastric body and antrum when micellar fat or bile was instilled in a Thiry loop of duodenum. These studies were performed while the animals were stimulated by food, acetylcholine, and 5-hydroxytryptophane (5-HTP). The latter two chemicals were infused for a 30-min. period. Micellar fat in the duodenum tended to decrease the frequency and amplitude of contractions only in those experiments using 5-HTP or the lower dose of acetylcholine (50 µg./kg./min.) as stimulants. This trend was not seen when bile alone or saline was placed in the duodenal loop. The data were evaluated by a motility index technic and analyzed by a paired comparison method.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.