Abstract
Bilateral subdiaphragmatic vagotomy leads to a marked decrease in hexokinase, glucokinase, glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase and lactate dehydrogenase activity in the soluble fraction of rat liver. The blood sugar level was unchanged at all times after the operation. These changes in enzyme activity evidently take place on account of the absence of parasympathetic impulses to the liver cell.
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