Abstract

The circadian rhythm of heart rate variability is present in normal subjects and in patients with angina, with the greatest variation in the normal population and a smaller but significant variation in the anginal group. With beta-adrenergic blockade, significant improvement occurs in all daytime time domain parameters, nocturnal percentage of RR intervals with >50-ms variation, and square root of mean-squared differences of successive RR intervals, daytime total power, and high-frequency band, representing significant improvement in parasympathetic function.

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