Abstract

Objectives: To assess the impact of atrial fibrillation on stroke severity and short-term (1 month) mortality. Materials and Methods: Totally 200 patients admitted to Ain Shams University Specialized Hospital were recruited and diagnosed clinically to have acute ischemic stroke within 3 days. Patients with hemorrhagic infarctions were excluded. History taking about previous heart disease was taken, full general and neurological examinations were done. Full metabolic profile, full cardiac investigations, carotid duplex, MRI brain stroke protocol with initial clinical evaluation and after 1 month re-evaluation using (NIHSS ) scale. Results: All patients underwent transthoracic echocardiography which revealed absence of “A” wave corresponding to atrial fibrillation in 33 patients (16.5%). Those Patients with atrial fibrillation had a median NIHSS score of 11.00 with IQR of 6.00 - 18.50 at admission and 6.00 with IQR of 2.00 - 14.50 after one month. Patients with atrial fibrillation showed significantly higher NIHSS at admission than patients in sinus rhythm, P

Highlights

  • Stroke continues to be a major health problem that ranks in the top three causes of death in most countries coming after ischemic heart disease and cancer

  • Hypertension and heart failure are most often associated with non-rheumatic atrial fibrillation

  • Subjects and Methods: A total of 200 patients admitted to Ain Shams university specialized hospital, stroke unit were recruited to this study between July 2009 and March 2011, diagnosed clinically to have acute ischemic stroke within 3 days

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Summary

Introduction

Stroke continues to be a major health problem that ranks in the top three causes of death in most countries coming after ischemic heart disease and cancer. It is responsible for a large burden of the population of neurological disorders [1]. Atrial fibrillation (AF) is a common cardiac arrhythmia, occurring in 5% - 10% of patients over 65 years of age, it occurs, in a paroxysmal form, in younger patients [4]. AF is one of the most common cardiac causes of stroke. In some patients no cause can be found, and this group is labelled as “lone” atrial fibrillation [6]

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