Abstract

Arsenite has been shown to increase biliary excretion of glutathione (GSH) in perfused rat liver (Anundi et al 1982). Therefore, the effect of arsenicals was studied on hepatobiliary disposition of endogenous non-protein thiols (NPSH) and the biliary excretion of compounds, such as mercurials (Ballatori and Clarkson 1983) and sulfobromophthalein (BSP), whose transport into bile is GSH-dependent.

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