Abstract
Sexual function in an important of the quality of life and subjective well-being in humans. Successful treatment of sexual dysfunction may improve not only sexual relationships, but also overall quality of life. The objective of this study was to determine the effects of Dendropanax morbifera (DM) Lev. leaf extracts on sexual behavior and testosterone levels in male rats. Three different doses of DM (50, 100, and 200 mg/kg/day) were administered orally for 28 days. On day 28 (final day of the sample treatment period) and day 42 (after 2 weeks of sample withdrawal period following 28 days of sample treatment), serum testosterone levels and sexual behavior of rats were determined, including mount frequency (MF), intromission frequency, mount latency (ML, the time from introduction of the female to the male to the first mount), intromission latency (IL), and post-ejaculatory interval (PEI). ML significantly reduced, whereas MF increased in the DM group. The DM group also had a reduced PEI. The oral administration of DM significantly increased serum testosterone levels compared with those in the control group. The results of this study demonstrate that an aqueous extract of DM represents a useful natural resource for the management of sexual function.
Highlights
Sexual function is an important component of quality of life and subjective well-being in humans
To investigate sustaining power, which is the ability for continuation of improved sexual function, we evaluated sexual behavior on day 14 after the withdrawal of Dendropanax morbifera (DM) treatment according to specific parameters of sexual behavior
mount frequency (MF) evaluated on days 28 and 42 of treatment is shown in Figure 2, and was found to be significantly increased in the DM 200 group (67.9 ± 1.17) on day 28, no significant change was observed on day 42
Summary
Sexual function is an important component of quality of life and subjective well-being in humans. Erectile dysfunction (ED) is one of the most common sexual dysfunctions in men [1]. The association between androgens and erectile function at the peripheral level has been established [2,3], with androgens acting on the central nervous system to serve as important modulators of male sexual behavior, including libido. The mechanisms leading to normal erectile function imply inter-connections among neurons, striated perineal muscles, and androgens, which are responsible for maintaining sexual behavior in adults. Several hundred years, men have used locally grown plants as supplements to energize, vitalize, and improve sexual function The mechanisms leading to normal erectile function imply inter-connections among neurons, striated perineal muscles, and androgens, which are responsible for maintaining sexual behavior in adults. or several hundred years, men have used locally grown plants as supplements to energize, vitalize, and improve sexual function
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