Effect of Aqueous Extract of Leek on Insulin and Biochemical Parameters in Female Rats

Abstract

Aim : study the change in level of insulin, cholesterol ,urea, creatinine and the weight of rats, when uptake orally of Aqueous Extract of (leek) for Female albino Rats. Methodology: Between march 2015 and January 2016, 20 female white rats They were randomized into two groups one of it is a control group and others treated with the aqueous extract warm of Allium porrum (leek) plants for concentration (800) mg/kg and taken for 1 month. This study was conducted in laboratories of physiology and chemistry at the faculty of pharmacollogy Medicine /University of Kufa. Results: It shows significantly increase (p 0.05) in the insulin hormone of white female rats for concentration 800 mg/kg comparing with control group, It also shown decrease (p 0.05) in the cholesterol level in plasma female rats for concentration 800 mg/kg which equaled with control group, and shown decrease (p 0.05) the weight of the rats. While the urea shows significantly decrease (p 0.05) the white female rats for concentration 800 mg/kg compared with control group. Conclusion: the creatinine shows significantly decrease (p 0.05) the white female rats for concentration 800 mg/kg compared with control group . In short comparing with control group. The aqueous of leek extract acts as increase insulin in white female rats while negative effect of aqueous extract of leek on Cholesterol, Urea and Creatinine and weight of the rats.