Abstract
Department of Applied Pharmacology, School of Pharmacy, Hebrew University, Jerusalem, Israel (Received 5th December 1974) Anti-ovine prolactin injected into the duct of a rabbit mammary gland inhibits the local lactogenic response of prolactin in the same duct (Saji & Crighton, 1968), and inhibits the proliferative effect of concurrently-injected prolactin in the pigeon crop-sac assay (Hayashida, 1962). Anti-ovine prolactin also decreases the weights of the prostate and seminal vesicle of male rabbits (Asano, Kanzaki, Sekiguchi & Tasaka, 1971). Anti-mouse prolactin has been reported to suppress the growth of mammary tumours in mice (Sinha, Lewis & Vanderlaan, 1974) and to inhibit the biological activity of mouse prolactin as measured by the pigeon crop-sac test (Kosugiyama, Mori & Nagasawa, 1970). Anti-rat prolactin injected into lactating rats lowered the progesterone secretion rate (Yoshinaga, 1973), while anti-human placental lactogen injected to pregnant rats during Days 1 to 5 of gestation reduced the weight of the
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