Abstract
Cryptosporidium parvum infection is a nearly ubiquitous infection in dairy herds for which there are no approved treatments or vaccines available in the US. Therefore, oral administration of immunoglobulins to control enteric disease in calves is of significant interest. Antibodies survive gastrointestinal transit, are accessible in the intestinal lumen, and remain locally active without the risk of violative residues. Our research team previously demonstrated that calves fed anti-11-10 IgY in milk had higher fecal pH, reduced respiratory disease, and increased frame measurements. Therefore, the objective of the current study was to carry out a dose-response trial evaluating the effects of feeding 0.5x, 2.0x, and lx the dose from the original study on respiratory and gastrointestinal health, C. parvum oocyst shedding, and calf growth.
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