Effect of AngioJet thrombectomy on renal function in patients with acute iliofemoral deep venous thrombosis

Abstract

Objective Investigate the effect of AngioJet thrombectomy on renal function in patients with acute iliofemoral deep venous thrombosis(DVT). Methods The data of patients with acute iliofemoral deep venous thrombosis who underwent AngioJet thrombectomy or catheter-directed thrombolysis (CDT) in our hospital from June 2015 to August 2018 were collected. Relevant clinical data within three days after operation were sorted out and the patients with acute kidney injury (AKI) were counted. The relationship between AngioJet thrombectomy and AKI in patients with acute iliofemoral DVT was analyzed by univariate regression analysis. Results There were 48 AngioJet thrombectomy patients and 50 CDT patients. There were no significant differences in average age, sex, diabetes mellitus, preoperative intravenous thrombolysis, serum creatinine and hematocrit (HCT) between both groups (P>0.05) . Conventional open surgery and reduction in HCT >10% could increase the incidence of AKI in patients after AngioJet thrombectomy treatment. Univariate regression analysis showed that AngioJet thrombectomy (OR=4.735, P=0.011) , conventional open surgery (OR=12.391, P 10% (OR=29.857, P<0.001) were independent risk factors for AKI after operation in patients with acute iliofemoral DVT. Conclusion AngioJet thrombectomy is an independent risk factor for AKI, and conventional traditional open surgery and reduction in HCT >10% can also increase the incidence of AKI. Key words: AngioJet thrombectomy; Acute iliofemoral deep venous thrombosis; Acute kidney injury; Risk factor