Year-end Sale % OFF 
Abstract
Hypertension is a known silent killer of both human and their close companion dogs, cats and horses. The disease becomes difficult to diagnose as anesthetics mask the actual reading of blood pressure of anaesthetized animal. The anesthetics Pentobarbital sodium, Ketamine and Xylazine alone and in combination are modifying the reading of mean arterial pressure (MAP). Hence, it becomes mandatory to know the effects of anesthetics on MAP. The rats were randomly divided into four groups viz. group-A (n=6), group-B (n=6), group-C (n=7) and group-D (n=5). The MAP of control rats of group A and B were measured under anesthetics Pentobarbital sodium and Ketamine and Xylazine in combination, respectively. However, the MAP of L-NAME-induced hypertensive rats of group-C and group-D were measured under anesthetics pentobarbital sodium and Ketamine and Xylazine in combination, respectively. The MAP of control rats of group-B significantly decreased under anesthetics Ketamine and Xylazine compared to rats of Pentobarbital group-A. Similarly, MAP of hypertensive rats of group-D significantly decreased under anesthetics Ketamine and Xylazine in combination to the level equivalence to MAP of group-A control rats indicting Ketamine and Xylazine combination significantly influencing the MAP of hypertensive rats. Hence, anesthetic combination of Ketamine and Xylazine should not be endorsed in animals since it masks the actual factual reading of MAP.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
