Abstract
The effect of an intrauterine foreign body (IUFB) on the incorporation of acetate-1- 14C into endometrial lipids, RNA and protein was studied in baboons. Thirty minutes after the intraluminal instillation of the radioprecursor, the control endometrium was found to contain about three times as much total radioactivity as the IUFB endometrium. However, the percentage of total tissue radioactivity which was incorporated into tissue macromolecules was 3–5 times greater in the IUFB than in the control endometrium. The tissue content of RNA and protein per unit tissue DNA was significantly lower and the specific activities of RNA and protein were significantly higher in the IUFB than in the control endometrium. These findings suggest that an IUFB may stimulate the turnover of macromolecules in baboon endometrium.
Published Version
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