Abstract

Effect of an Aqueous Extract of Fenugreek (Trigonella Foenum Graecum) seeds on Hyperglycemia Induced with Alloxan

Highlights

  • For long times, the people looked for drugs in nature

  • To evaluate antidiabetic effects of Fenugreek seeds extract on Alloxan-induced diabetic mice

  • Mice were injected with subcutaneous injection 180mg/kg body of freshly prepared of Alloxan and Diabetes mellitus confirmed by testing blood glucose, and mice with blood glucose level of ≥200mg/dl were considered as diabetic

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Summary

Introduction

The people looked for drugs in nature. In clinical study, increased insulin sensitivity was observed in fenugreek recipients, and in another one, with newly-diagnosed type-2 diabetes mellitus, serum triglycerides were reduced in patients who received a hydroalcoholic extract of fenugreek seeds 1g/day [3]. The aim of this study to investigate antidiabetic effects of local Fenugreek seeds extract on Alloxan-induced diabetic mice. Diabetes mellitus is a metabolic disease that causes high blood sugar. The number of people suffering from the disease worldwide is increasing at an alarming rate. Fenugreek (Trigonella foenum-graecum) is an herb long used in alternative medicine. These benefits may be due to fenugreek’s role in improving insulin function

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