Abstract
The possibility of amino acids acting as ternary complexation agents for the binding of pyrene with β-cyclodextrin (β-CD) was investigated. UV−vis absorption measurements combined with steady-state and time-resolved fluorescence studies were employed to characterize ternary complex formation. From the 18 amino acids tested it was determined that tryptophan, leucine, phenylalanine, methionine, and isoleucine form ternary complexes. The first three also significantly enhance the association constant of pyrene with β-CD. Amino acids are less efficient than alcohols in enhancing the association constants of host−guest complexes, but a higher degree of steric constraint in the complexes including these zwitterionic molecules was observed. In addition, two types of pyrene−β-CD complexes were shown to exist, which were assigned to complexes with 1:1 and 1:2 pyrene:β-CD stoichiometries.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
