Effect of aluminium oxyhydroxide nanoparticles on the structure and properties of the calcium phosphate coatings

Abstract

Modification of calcium phosphate (C-P) based biocoatings with aluminum oxyhydroxide AlO(OH) nanoparticles and its effect on their morphology, structure, phase composition, wettability, electrical and biological properties are studied. C-P coatings were formed on the titanium substrate by the microarc oxidation (MAO) method in the acidic electrolyte. Porous calcium-phosphate coatings were functionalized by aluminum oxyhydroxide nanoparticles by hydrolysis reaction in aqueous suspension of AlN nanopowder. The increase ultrasonic dispersion duration of AlN suspension up to 60 min provides more uniform distribution of AlO(OH) on the coating surface. The introduction of positively charged AlO(OH) nanoparticles has been unveiled to increase zeta potential value of the coating surface. The antimicrobial activity of the C-P coating rises by 27% after the introduction of AlO(OH) nanoparticles and the proliferation of L929 cells on the coatings functionalized by the nanoparticles grows by 25%. The results obtained demonstrate the aluminum oxyhydroxide nanoparticles introduction significantly improve the functional properties of the C-P coatings.