Abstract
Stroke volume and cardiac output are accurately estimated by Doppler echocardiographic methods that rely on inflow velocities and orifice area of the mitral valve. 1,2 Changes in inflow velocities represent changes in flow, but this requires the assumption of a stable mitral anulus area. It is known that the anulus area decreases by an estimated 20 to 50% during systole, 3,4 but there are few data on the effect of altered filling on the anulus. This study determines the effects of flow increased with dobutamine or decreased with phenylephrine on the mitral anulus.
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