Abstract
Diabetes mellitus refers to a predominant concern characterized by excessive glycemia, glycosuria, as well as hyperlipemia; resulting from deficiency of insulin. Plants have always been paid attention as suitable substitutes for chemical drugs due to easy accessibility, fewer side effects, low-toxicity, and cost-effectiveness exhibiting reportedly helpful effects. In the present study, Alloxan monohydrate 150mg/kg body weight was administrated intraperitoneally to induce diabetes in rats, the effect of Aloe vera leaf gel and Metformin on blood glucose and body weight were compared. Aloe vera gel in a concentration of 1000mg/kg body weight and metformin at concentration 150mg/kg body weight was orally administered in induced diabetic in rats. There was a significant difference of (p<0.05) recorded in blood glucose level and body weight in the control and treated groups. The glucose level in blood was decreased in all treated groups (aloe vera treated group and metformin-treated group) except control diabetic group: whereas after induction of diabetes bodyweight of all diabetic groups were decreased. After treatment with aloe vera and metformin, there was a significant increase in body weight of treated groups as compared with the diabetic control group. Keywords: Aloe vera; Blood glucose; Metformin http://dx.doi.org/10.19045/bspab.2020.90226
Highlights
Introduction mellitus, commonly known as typeI and Diabetes mellitus is a predominant concern type-II [3]
Metformin used for the treatment of type -II diabetes mellitus, and it has been suggested as an effective therapy for the patient suffered from type I diabetes mellitus, as it facilitates the releasing of insulin from (β) beta cells of the pancreas and including weight reduction, enhanced lipid profiles and improved endothelial function [14, 15]
There was a statistically significant rise in glucose level in the blood of diabetic control group compared to the control non-diabetic group (p
Summary
The therapeutic effect of Aloe vera and Metformin on glucose level and body were studied. 200 grams were selected as a model. Rats were tagged and kept in cages one week before study at the animal house
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
