Abstract
Objective To investigate the effect of all-in-one nursing intervention on the stress response and postoperative quality of life in patients following esophageal cancer surgery .Methods From the October 2012 to March 2013 , 62 patients with radical operation of esophageal carcinoma were divided into all-in-one nursing intervention group （32 cases） and the routine nursing group （30 cases）.The blood samples of the two groups of patients were collected before operation （surgery day） （T0） and on the fifth day after operation （T1） to measure stress response indicators , including fasting blood glucose （ FBG ） , C-reactive protein （ CRP ） , interleukin -6 （IL-6）, plasma cortisol （Cor）.And using European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-30 （ QOL ） evaluated the early quality of life , before operation and the second week after opreation .Results The stress reaction index before operation had no significant difference between two group （P〉0.05）.On the fifth day after operation, the FBG, CRP and Cor levels of two groups were significantly higher than the preoperative level （t=3.724,7.203,4.137, respectively;P〈0.05）, but there was no significantly difference in the IL-6 level （t =0.452,P〉0.05）.The FBG, CRP, IL-6 and Cor levels of two groups on the fifth day after operation were significantly higher than the preoperative level （ t =3.031,5.361,2.864,3.534,6.990,10.755,2.415,8.166, respectively;P〈0.05）.Scores of each function item and symptom before operation had no significant difference between the two groups （P〉0.05）.And two weeks after the operation , the functions of the research group were higher than those in the control group （ P〈0.05 ） .Symptoms scores of study group was lower than those in the control group , and there were statistically significant differences in seven aspects （ P〈0.05）, but the other two aspects had no significant differences （P〉0.05）.Conclusions All-in-one nursing intervention can significantly reduce stress reaction and improve the quality of life in postoperative patients with esophageal cancer . Key words: Esophageal tumour; Stress response; Quality of life; All-in-one nursing
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