Abstract

Five mg of either a crude extract of seeds of ololiuqui or a mixture of synthetic alkaloids caused drowsiness in former morphine addicts but few other subjective effects. Perceptual distortion was reported only rerely, and hallucinations did not occur. In contrast, LSD-25 caused nervousness, perceptual distortion, euphoria and hallucinations. The alkaloids of ololiuqui did not cause fever or marked mydriasis. Ololiuqui and the alkaloids of ololiuqui should be regarded principally as sedatives rather than as psychotomimetics.

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