Abstract

Age is a major risk factor for cardiovascular disease and older Americans are the fastest growing segment of the population. The need to understand physiological changes with aging is essential for better prevention and treatment of cardiovascular disease. This mini-symposium will address how aging impacts three neural cardiovascular reflexes. First, Kevin D. Monhan, Ph.D. will present data related to how integrative baroreflex function is altered by aging. This will include examination of both the cardiovagal and sympathetic limbs of the baroreflex and possible sites of age-associated dysfunction within the reflex. This presentation will be followed by a talk by Lawrence I. Sinoway, M.D. who will discuss skeletal muscle reflexes and exercise blood flow adjustments observed with aging. The last presentation will be given by Chester A. Ray, Ph.D. who will address how aging modifies cardiovascular reflex control via the vestibular system. The vestibular system is well known for its contribution to balance but recent data indicate it contributes importantly to sympathetic nerve activity and orthostatic blood pressure regulation.

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