Abstract
Atherosclerosis, the major cause of cardiovascular disease (CVD), is the abnormal deposit of cholesterol within the intima of the arterial wall. Conversely, in epidemiologic studies investigators have estimated that normal aging (arteriosclerosis) produces an annual thickening of the media of the arterial wall by >0.01 mm per year. An indirect method of diagnosing atherosclerosis involves ultrasound analysis of the common carotid intima-media (CCIMT) wall. The Atherosclerosis Center specializes in aggressive management of CVD risk factors. The Center performs serial CCIMT analysis with a computerized edge-detection ultrasound device (MICROMAXX, Sonosite) to monitor the progression of atherosclerosis. The device measures 100 markers within a 1-cm area of the CCIMT wall, 1 cm proximal to the bulb, to provide the mean and max thickness. The device also contains carotid ultrasound data of healthy people (ages 10−90 years), allowing comparison of IMT values with those of clinical patients.
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