EFFECT OF AGE AND BMI ON PREGNANCY OUTCOME IN PATIENTS UNDERGOING IUI

Abstract

Introduction: Intrauterine insemination (IUI) is the rst line of assisted conception method, which has been widely used for the treatment of subfertility couples. It is a technique in which the semen is processed into highly concentrated motile sperm and inseminated into the uterus through the cervix using a ne catheter. It is often suggested to infertile couples of which the woman has at least one patent fallopian tube. Many prognostic factors are associated with successful pregnancy in IUI cycles e.g., younger female age, higher total motile sperm per ejaculate, better ovarian reserve, and more number of dominant follicles. The present study aims to study the inuence of female's age and body mass index on pregnancy rates following IUI procedure. This retros Methodology: pective observational study was done from June 2021 to June 2022 on 60 couples who underwent IUI at KVGMCH, sullia. The patients included in the study were aging between 19- 45 years. Weights and heights of women were recorded and BMI was calculated. They were classied into 4 BMI categories. The IUI procedure was carried out and pregnancy outcome was measured as positive urine pregnancy test. The overall pregnancy rate after IUI in the study Results: group was 15%. Highest pregnancy rate of 18.75%, was observed in the age group of 31-35 years, as compared with 10% pregnancy rate among 41-45 years. However this difference was not statistically signicant (p-0.9877),one pregnancy occurred at 42 years among 10 women over 41 years of age, whereas 3 pregnancy occurred among 16couples. BMI was calculated and tabulated according to WHO denition. The highest pregnancy rate was observed as 20% for BMI >/ 35, while the lowest pregnancy rate was 12.5% with the BMI from 18.5 to 25.5. This difference was also not statistically signicant( p-0.96992). Conclusion: The study concludes that IUI improves the chances of pregnancy in unexplained infertility. The efcacy of IUI is highest in middle age and efciency declines after the age of 45years. Pregnancy outcome is independent of BMI of women