Abstract

Capillary filtration rate and capillary filtration coefficient have been measured in the forearm of man in control limbs and in limbs subjected to iontophoresis of adrenaline to minimize superficial blood flow. Gross reduction in the rates of tissue fluid accumulation occurred in the iontophoresed limbs. It is concluded that the skin and subcutaneous tissues—that is, the tissues whose vessels are accessible to vasoconstriction by adrenaline administered by ion transfer—are the major site for accumulation of extracellular fluid in the forearm in man.

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