Abstract
Cyclamate is one of the artificial sweeteners that is still often consumed by the public as a food or beverage additive. In some countries, cyclamate is prohibited for consumption because it is carcinogenic. This study was conducted to determine the effect of sodium cyclamate on the number of polymorphonuclear cells (PMN). The type of research used was a laboratory experimental. The sample used was a male rat totaled of 25 which were divided into 5 treatment groups which was without sodium cyclamate, administered sodium cyclamate at a dose of 4.5 mg / 200 g BW, administered sodium cyclamate at a dose of 9.5 mg / 200 g BW, administered sodium cyclamate at a dose of 14.5 mg / 200 g BW, and administered sodium cyclamate at a dose of 19, 5 mg / 200 g BW. The research finding revealed the statistical significancy for p<0.05 indicated that there was an effect of sodium cyclamate to the number of polymorphonuclear cells. The usage of sodium cyclamate is known to generate oxidative stress, which results in cell damage and leukocytosis.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
