Abstract
Adiponectin is protein secreted from adipose tissue and plays important role in regulating glucose level as well as fatty acid breakdown. Adipose tissue has been considered an important endocrine organ. Adiponectin has been shown to completely reverse insulin resistance. A total of sixty subjects involved in this study to examine the regulatory roles of adiponectin concentration in diabetic type II postmenopausal women and to study the correlation between the parameters (serum glucose, cholesterol and triglyceride). Thirty of each diabetic women (BMI<30) and healthy postmenopausal women (BMI<30) were selected from Baghdad teaching hospital in Baghdad/ Iraq. ELISA (enzyme linked immune sorbent assay) technique was used for the measurement of serum adiponectin. Blood glucose, cholesterol and triglyceride were determined by using colorimetric method. Results showed that the level of serum adiponectin in diabetic postmenopausal women were significantly (P < 0.01) lower than that of non diabetic postmenopausal women. Serum glucose in diabetic postmenopausal women was significantly (P < 0.01) higher than non-diabetic women. The present study indicates the possibility of future development of new anti-diabetic agents that act independent of insulin action.
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