Abstract
Abstract Data concerning the effect of intramuscular injection of 5-adenylates and related compounds on the level of ATP in the blood of normal and diseased persons are presented. Ten milligrams or more in aqueous solution and 20 milligrams in gelatine produced in most healthy subjects a significant elevation above the level established as normal. Like dosage of the aqueous solution produced no alteration in the level of a large percentage of persons with Hodgkin's disease and, when occurring at all, the rise was much less than that which occurred in members of the normal group. There were even a few persons in this group whose blood showed diminished ATP after dosage. Findings for a small group of persons with various diseases paralleled those of a group afflicted with Hodgkin's disease.
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