Abstract

risk based guidelines were used as compared to using the current Danish guidelines. Methods.– Female patients attending a falls clinic and evaluated by bone mineral density bone densitometry and referred for bone densitometry were studied. 10-year fracture risks were calculated using the Garvan Fracture Risk Calculator and FRAXrax (WHOFracture Risk Assessment Tool). tools. PercentagePercentages of patients eligible for treatment wereas determined using fourusing four guidelines: Danish Bone Society (DBS), the FRAX based age-dependent UK National Osteoporosis Guideline Group (NOGG), the US National Osteoporosis Foundation FRAX based 3% (hip)/20% (any) cut) cut-off guidelinesoff guidelines (US-FRAX) and the Australian Garvan derived 20% cut-off guidelines (Garvan). Results.– Median age [IQR] of patients (n=85) was 81 years ([IQR=75–85]). Mean 10-year % risk (SD) of major/any osteoporotic fractures wererisk (SD) ofmajor/any osteoporotic fractures was: DK-FRAX 29.8% (12.8), UK-FRAX 19.9% (9.5), US-FRAX 21.8% (10.3), Garvan 50.2% (23.8). Proportion of patients (95%CI) eligible for treatment were:wasere; DBS 55.3% (44.7–65.9), NOGG 51.2% (40.5–61.9), US-FRAX 87.1% (80.0–94.2), Garvan 90.6% (84.4–96.8). Conclusion.– These data show that the choice of guideline has a major impact on treatment decisions in this group of older Danish women with falls. Adherence to the US-FRAX and Garvan algorithms would result in extremely discrepant treatment rates compared to adherence with the DBS and UK-NOGG guidelines.

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