Abstract
It is known that antibody production can take place without the adrenal cortical hormones. This was shown some years ago by several investigators (Jaffe & Marine, 1924, Perla & Marmorston-Gottesman, 1928, Marmorston-Gottesman & Perla, 1929, Khorazo, 1931) and has recently been confirmed by others (Murphy & Sturm, 1947, Eisen et al., 1947, Roberts & White, 1951), who all found that antibody production with different antigens in adrenalectomized animals, chiefly rats and rabbits, was of the same order of magnitude as in normal animals. It can thus scarcely be expected that adrenal cortical hormones should play any predominant rôle in the synthesis of antibodies.
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