Abstract
Acetamiprid is one of the most wide used insecticides over the entire world. Three acetamiprid concentrations, the dependence one (200 ppm) and two other high concentrations (300 and 400 ppm) were used to treated tomato fruits at the final stage of ripening. A daily samples up to 15 days, were examined for their acetamiprid residues. The maximum migration of acetamiprid (systemic) into tomato fruit was observed after three days (1.7, 1.89 and 2.27ppm) of spraying by 200, 300, and 400 ppm. After 7 days of application, the acetamiprid residues are more than five-fold of the Maximum Residue Limit (acetamiprid MRL=0.2 mg/kg). Four groups of male mice (each of 10, control and three treatments) were used to study the effects of acetamiprid on some blood profile parameters. Three selected concentrations of acetamiprid 32, 64 and 128 ppm were used to orally administrate the male mice (0.0064, 0.0128 and 0.0256 mg/mouse daily respectively) under controlled conditions for 28 days. It was found that there was a direct relationship between acetamiprid concentrations and triglycerides, total cholesterol, LDL, VLDL, catalase, malondialdehyde, urea, creatinine, AST, ALT and superoxide dismutase level. While, reverse relationships were observed with HDL, LH, FSH, testosterone and acetyl cholinesterase
Highlights
Pesticide is any substance or a mixture of substances intended for preventing, destroying, repelling or mitigating any pest.Pesticides vary greatly in toxicity, persistence in the environment, and ability to bioaccumulate up the food chain
All pesticides are regulated by the Environment Pesticides Agency (EPA) which regulates the sale and use of pesticides through product registration and labeling so as to prevent unreasonable adverse effects on people and environment [15]
Four concentrations of acetamiprid (0, 32, 64 and 128 ppm) have been prepared. This range of acetamiprid was associated with its residues in tomato fruits at the end of the field experiment
Summary
Pesticide is any substance or a mixture of substances intended for preventing, destroying, repelling or mitigating any pest.Pesticides vary greatly in toxicity, persistence in the environment, and ability to bioaccumulate up the food chain. Most pesticides can cause severe illness or even death if misused, but every registered pesticide can be used safely.Two types of pesticide toxicity (or damage) often are mentioned: acute and chronic. Acute effects are those resulting from a single exposure. They usually are noted within a few minutes to several days. Chronic effects result from repeated low-level exposure and often do not manifest themselves for decades [13]. Acetamiprid group of insecticides are the most highly effective and largest selling insecticides worldwide for crop protection. In the present paper the effect of acetamiprid residues in tomato fruits on some parameters of blood profile in male mice were studied
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