Abstract
This study was performed to investigate the preventing effects to liver injury of Acer tegmentosum Maxim. extract (ATE). After oral administration ATE to SD rats, liver injuries were induced by CCl4, galactosamine or ethionine treatments. The aspartate aminotransferase (AST), alanine aminotransferase (ALT), triglyceride and cholesterols in blood were used as indicators of liver damage. When acute hepatitis was induced by CCl4 or galactosamine, ATE-fed rats showed low level of AST and ALT in plasma than the ATE-unfed rats. In case of ethionine-induced fatty liver, the triglyceride in plasma were shown to reduced level in ATE-fed rats than ATE-unfed rats. These results indicate that Acer tegmentosum Maxim. extract protected hepatic failure.
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